Node negative breast cancer recurrence rates

In fact, it must be considered that many of the published trials on node-negative small tumors reporting very favorable RFS have small sample size, or too short follow-up; studies with longer follow-up periods, reporting 10, 15, year RFS, suggest a continued risk of late relapse Black et al. Grade 3 was found in Recurrences and deaths are known to occur, even if less frequently, in small, node-negative breast cancer patients, and decision on adjuvant treatments remains controversial. Published by Elsevier Inc.

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Recurrence risk in small, node-negative, early breast cancer: a multicenter retrospective analysis

Minimal and small size invasive breast cancer with no axillary lymph node involvement: At the median follow-up time of Recent knowledge suggest that breast cancer is a heterogeneous disease, with some characteristics, such as Her-2, hormonal receptors, and other variables being a fundamental and critical determinants of clinical outcome, with high prognostic value Foulkes et al.

Node negative breast cancer recurrence rates
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Patients were divided into three groups according to their combined hormonal receptor and Her-2 status: We retrospectively identified pT1N0 breast cancer patients who received surgery between and in four Italian oncologic centers. At multivariate analysis, histologic grade and Ki resulted independent prognostic factors. Histologic grade and biological features were evaluated on the invasive component of the tumor. Pathologic data were obtained by collecting and reviewing pathology reports on tumor size, histologic subtype, modified Bloom-Richardson histologic grade.

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Node negative breast cancer recurrence rates
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Node negative breast cancer recurrence rates

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